Chaaban Lab

Publications

Google Scholar profile
Structural basis of dynein interaction with diverse activating adaptors
d'Amico EA, Chaaban S, Abid Ali F, Michalski L, Carter AP.
bioRxiv (Accepted in Nature Structural & Molecular Biology) - 2026
Structures of dynein-dynactin complexes assembled with diverse activating adaptors
Science Advances cover featuring Asgard archaea research
Asgard archaea reveal the conserved principles of ESCRT-III membrane remodeling
Souza DP*, Espadas J*, Chaaban S*, Moody ERR, Hatano T, Balasubramanian M, Williams TA, Roux A, Baum B.
Science Advances - 2025
Asgard archaea ESCRT-III membrane remodeling figure
Dynein microtubule-binding domain visualization
A force-sensitive mutation reveals a non-canonical role for dynein in anaphase progression
Salvador-Garcia D, Jin L, Hensley A, Golcuk M, Gallaud E, Chaaban S, Port F, Vagnoni A, Planelles-Herrero VJ, McClintock MA, Derivery E, Carter AP, Giet R, Gur M, Yildiz A, Bullock SL.
Journal of Cell Biology - 2024
Protein structure prediction visualization
Navigating protein structure prediction in the era of machine learning
Chaaban S*, Ratkevičiūtė G*, Lau C*.
The Biochemist - 2024
Nature cover featuring dynein-dynactin structure
Structure of dynein-dynactin on microtubules shows tandem adaptor binding
Chaaban S, Carter AP.
Nature - 2022
Dynein-dynactin structure on microtubules
PACRG-MEIG1 complex structure
Crystal structure of human PACRG in complex with MEIG1 reveals roles in axoneme formation and tubulin binding
Khan N, Pelletier D, McAlear TS, Croteau N, Veyron S, Bayne A, Black C, Ichikawa I, Khalifa AAZ, Chaaban S, Kurinov I, Brouhard GJ, Bechstedt S, Bui KH, Trempe J-F.
Structure - 2021
Cover featuring C. elegans tubulin study
The structure and dynamics of C. elegans tubulin reveals the mechanistic basis of microtubule growth
Chaaban S, Jariwala S, Hsu C-T, Redemann S, Kollman JM, Muller-Reichert T, Sept D, Bui KH, Brouhard GJ.
Developmental Cell - 2018
C. elegans tubulin structure
Microtubule bestiary cover
A microtubule bestiary: structural diversity in tubulin polymers
Chaaban S, Brouhard GJ.
Molecular Biology of the Cell - 2017
Microtubule bestiary figure
Diazonamide DZ-2384 microtubule curvature study
The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity
Wieczorek M, Tcherkezian J, Bernier C, Prota AE, Chaaban S, Rolland Y, Godbout C, Hancock MA, Arezzo JC, Ocal O, Rocha C, Olieric N, Hall A, Ding H, Bramoulle A, Annis MG, Zogopoulos G, Harran PG, Wilkie TM, Brekken RA, Siegel PM, Steinmetz MO, Shore GC, Brouhard GJ, Roulston A.
Science Translational Medicine - 2016
Microtubule nucleation cover
Microtubule-associated proteins control the kinetics of microtubule nucleation
Wieczorek M, Bechstedt S, Chaaban S, Brouhard GJ.
Nature Cell Biology - 2015
Macromolecular crowding cover
Macromolecular crowding pushes catalyzed microtubule growth to near the theoretical limit
Wieczorek M*, Chaaban S*, Brouhard GJ.
Cellular and Molecular Bioengineering - 2013