Francis Crick Institute · London

Chaaban Lab

Lab opens January 2027

Explore our research

How do cells organize and reshape themselves?

Cells rely on their internal scaffolding, the cytoskeleton, and molecular motors to organise their contents, change shape and divide.

We want to understand how these systems work together, and how their activity is coordinated with the reshaping of cell membranes.

A central focus is the final stages of cell division: building the bridge between daughter cells and making the cut that separates them.

Building
the bridge

How do cells organise their internal scaffolding to position the machinery that separates daughter cells?

Making
the final cut

How do molecular machines reshape the membrane and cytoskeleton to complete division?

Sami Chaaban
Sami Chaaban